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Fig. 9 | Cancer Cell International

Fig. 9

From: Exosomes from tamoxifen-resistant breast cancer cells transmit drug resistance partly by delivering miR-9-5p

Fig. 9

The schematic representation of the molecular mechanism miR-9-5p in TAM-resistant BC cells. In TAM-resistant BC cells, miR-9-5p promotes TAM resistance by negatively regulating ADIPOQ, whereby it promotes BC cell viability and inhibits apoptosis. In addition, miR-9-5p can be packaged into the exosomes derived from TAM-resistant BC cells, and transferred into the TAM-sensitive BC cells

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Cancer Cell International

ISSN: 1475-2867

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