Fig. 3
From: Circ_0015756 promotes the progression of ovarian cancer by regulating miR-942-5p/CUL4B pathway
Circ_0015756 acts as a miR-942-5p sponge. a Three websites (circBank, Starbase 3.0 and circinteractome) were used to predict potential miRNAs that might bind to circ_0015756. b After transfection with si-circ_0015756, the levels of four possible targets (miR-942-5p, miR-145-5p, miR-149-5p and miR-224-5p) were detected. c The putative binding site between circ_0015756 and miR-942-5p was depicted by circinteractome. d The overexpression efficiency of miR-942-5p was detected by qRT-PCR. The binding relationship between circ_0015756 and miR-942-5p was verified by dual-luciferase reporter assay (e, f), RIP assay (g, h) and RNA pull-down assay (i) in OV90 and SKOV3 cells. j The level of miR-942-5p was determined in OV90 and SKOV3 cells transfected with si-NC or si-circ_0015756. k, l The expression of miR-942-5p in OC tissues and cells was tested by qRT-PCR. *P < 0.05