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Fig. 1 | Cancer Cell International

Fig. 1

From: DLG1-AS1 is activated by MYC and drives the proliferation and migration of hepatocellular carcinoma cells through miR-497-5p/SSRP1 axis

Fig. 1

DLG1-AS1 promotes HCC cell growth and migration. a The expression of DLG1-AS1 was tested in HCC cell lines (MHCC97-L, Huh-7, Hep3B and HCCLM3) and in the normal Human liver immortalized cell line (THLE-2). b The efficiency of DLG1-AS1 knockdown was analyzed via RT-qPCR in Hep3B and HCCLM3 cells. c, d The proliferative ability of Hep3B and HCCLM3 cells transfected with sh-DLG1-AS1#1/2 or sh-NC was evaluated via colony formation and EdU assays. e, f Cell apoptosis rate in different groups was analyzed by TUNEL assay and flow cytometry analysis. g, h Transwell assays were performed to measure the capabilities of migration and invasion. *Pā€‰<ā€‰0.05, **Pā€‰<ā€‰0.01

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