Peritumoral plasmacytoid dendritic cells predict a poor prognosis for intrahepatic cholangiocarcinoma after curative resection

Table 2 Correlation between intratumoral and peritumoral plasmacytoid dendritic cells (pDCs) and clinicopathologic characteristics in ICC (n = 359 for intratumoral tissues, 322 for peritumoral tissues)

Clinicopathological indexes	Intratumoral pDCs			Peritumoral pDCs
Clinicopathological indexes	Low	High	P	Low	High	P
Age (year)
≤ 50	32	42	0.242	32	36	0.625
> 50	145	140		128	126
Sex
Female	85	68	0.041	75	61	0.094
Male	92	114		85	101
HBsAg
Negative	124	128	0.955	110	116	0.576
Positive	53	54		50	46
CA199
≤ 36	78	71	0.331	78	59	0.025
> 36	99	111		82	103
AFP (ng/ml)
≤ 20	157	160	0.816	145	141	0.307
> 20	20	22		15	21
GGT (U/L)
≤ 54	80	92	0.310	89	67	0.010
> 54	97	90		71	95
Liver cirrhosis
No	138	135	0.400	120	127	0.471
Yes	39	47		40	35
Tumor size (cm)
≤ 5	74	85	0.351	84	61	0.007
> 5	103	97		76	101
Tumor number
Single	130	128	0.511	122	107	0.043
Multiple	47	54		38	55
Vascular/bile duct invasion
Absence	132	150	0.070	134	121	0.045
Present	45	32		26	41
Lymphatic metastasis
No	152	154	0.736	145	132	0.018
Yes	25	28		15	30
Tumor encapsulation
Complete	37	25	0.072	32	23	0.167
None	140	157		128	139
Tumor differentiation
I + II	93	88	0.427	90	79	0.179
III + IV	84	94		70	83
TNM stage
I	90	92	0.955	97	70	0.002
II + III + IV + IV	87	90		63	92

The italic numerals indicate P value < 0.05
AFP alpha-fetoprotein, GGT gamma glutamyl transferase, CA 19-9 carbohydrate antigen 19-9, TNM tumor-node-metastasis
Chi square tests for all analyses

ISSN: 1475-2867