Fig. 1

LncRNA LINC01194 is given to high expression and promotes malignancy in LUAD. a LINC01194 expression was detected by qRT-PCR in normal human bronchial epithelioid cell line (16HBE) and LUAD cell lines (A549, PC-9, HCC827, NCI-H1975 and NCI-H1299). b qRT-PCR was applied to access the interference efficiency of LINC01194 in A549 and HCC827 cells. c, d Colony formation assay and EdU assay showed that down-regulation of LINC01194 significantly decreased LUAD cell proliferation. e Transwell assay was utilized to detect the ability of LUAD cells migration and invasion. f, g The apoptosis of LUAD cells was accessed by TUNEL assay and flow cytometry analysis. All results were displayed as the mean ± SD, n = 3, Student’s t test or one-way analysis of variance was carried out for evaluating the differences between groups. *P < 0.05, **P < 0.01