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Fig. 1 | Cancer Cell International

Fig. 1

From: Metapristone (RU486-derivative) inhibits endometrial cancer cell progress through regulating miR-492/Klf5/Nrf1 axis

Fig. 1

Metapristone inhibited endometrial cancer cell growth and promoted endometrial cancer cell apoptosis. a Cell growth curves by MTT assay of RL95-2 cells and Ishikawa cells with metapristone (50 μM) treatment. Ethanol-treated cells were as control. Results represent mean ± SD (n = 6). b Cell colony formation of RL95-2 cells and Ishikawa cells with metapristone (50 μM) treatment. Ethanol-treated cells were as control. Values are mean ± SD (n = 3 per group). c EdU assay was used to detect the cell proliferation phenotype with the treatment of ethanol or metapristone (50 μM 48 h). d The protein level of Cleaved-Caspase 3, Cleaved-Caspase 9, Bax and Bcl-2 in RL95-2 cells and Ishikawa cells with ethanol or metapristone treatment were detected by western blot. GAPDH was used as the control

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Cancer Cell International

ISSN: 1475-2867

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