Fig. 5
From: SKP1 promotes YAP-mediated colorectal cancer stemness via suppressing RASSF1
Knockdown of YAP abolished the effect of SKP1 on the stemness of colorectal cancer cells. a–d Knockdown of YAP abolished the effect of SKP1 on the stemness of colorectal cancer cells. The sphere-forming capacities (a), the frequency of sphere-forming cells (b), the migration capacity (c), the expression of cancer stem cells and EMT markers (d) in indicated cells were analyzed by sphere formation (a), limiting dilution assay (b), transwell (c) and qRT-PCR assay (d), respectively. Student’s t-test (***p < 0.001)