Fig. 2
From: YAP manipulates proliferation via PTEN/AKT/mTOR-mediated autophagy in lung adenocarcinomas
YAP targeted siRNA suppresses YAP expression in A549 and H1299 cells with reducing cell proliferation. a The result of biological pathway enrichment analysis was shown with respect to YAP. b siYAP-1/2 was constructed and significantly inhibited the expression of YAP in A549 cells, which detected by qPCR and Western blot. c The protein expression of YAP in A549 transfected with siYAP or pcDNA3.1-YAP, and H1299 with siYAP transfection were analysed by Western blot, respectively. d CCK-8 assay was utilized to analyze cell proliferation of A549 cells with siYAP or pcDNA3.1-YAP, and H1299 with siYAP transfection. Data represent the Mean ± SD on three independent experiments (one-way ANOVA, **P < 0.01, ***P < 0.001)