Skip to main content
Fig. 6 | Cancer Cell International

Fig. 6

From: Circular RNA circPLK1 promotes breast cancer cell proliferation, migration and invasion by regulating miR-4500/IGF1 axis

Fig. 6

MiR-4500 exerted its anti-cancer effects in BC cells by targeting IGF1. BT549 and HCC38 cells were transfected with miR-NC, miR-4500, miR-4500 + pcDNA3.0-NC, or miR-4500 + pcDNA3.0-IGF1. a Cell viability was assessed by CCK-8 assay. b Flow cytometry was applied to analyze the cell cycle distribution. c, d Western blot assay was performed to measure the protein levels of CDK4 and CDK6. e, f Transwell assay was employed to determine cell migration and invasion. ***P < 0.001

Back to article page

Cancer Cell International

ISSN: 1475-2867

Contact us