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Fig. 8 | Cancer Cell International

Fig. 8

From: Circular RNA circPLK1 promotes breast cancer cell proliferation, migration and invasion by regulating miR-4500/IGF1 axis

Fig. 8

CircPLK1 knockdown repressed tumor growth via upregulating miR-4500 and downregulating IGF1. Sh-NC or sh-circPLK1-transfected HCC38 cells were introduced into nude mice to establish mice model. a, b The data of tumor volume and weight were recorded and graphed. c The expression levels of circPLK1 and miR-4500 were measured by qRT-PCR in excised tumor tissues. d The protein expression of IGF1 was determined by western blot assay in excised tumor tissues. ***P < 0.001

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Cancer Cell International

ISSN: 1475-2867

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