Fig. 1

ATF2 expression is elevated in LUAD. a ATF2 expression in various cancers and corresponding normal tissues from the GEPIA database. Red column, cancer tissues; blue column, normal tissues. b ATF2 expression in LUAD tissues and normal lung tissues from TCGA database. Normal, n = 59, LUAD, n = 533. c ATF2 expression in paired LUAD tissues and normal lung tissues from TCGA database. Normal, n = 57, LUAD, n = 57. d ATF2 expression in primary and recurrent LUAD tissues from TCGA database. Primary, n = 513, Recurrence, n = 20. e ATF2 protein expression in LUAD and normal lung tissues based on CPTAC data from ULCAN cancer database. Normal, n = 111, LUAD, n = 111. f ATF2 expression in LUAD and normal lung tissues was detected by qRT-PCR. Normal adjacent lung tissues (NAT), n = 25, LUAD, n = 31. g ATF2 expression in lung cancer cell lines and normal bronchial epithelial cell line was detected by qRT-PCR. h Kaplan–Meier analysis for investigating the correlation of ATF2 expression with disease-free survival (DFS) in LUAD patients from GEPIA database. Low ATF2, n = 239, High ATF2, n = 239. ^*P < 0.05, ^**P < 0.01