Fig. 4

ATF2/NEAT1 axis is involved in the progression of LUAD. a Relative expression of NEAT1 was detected by qRT-PCR after transfection with NEAT1-overexpressing vector and empty vector in LUAD cells. b Cell viability of LUAD cells was detected by CCK8 assay after transfection as indicated. c Colony formation ability of LUAD cells was detected after transfection as indicated. d Invasion ability of LUAD cells was detected by transwell invasion assay after transfection as indicated. e A photograph of the tumors collected from nude mice in the shATF2 and shNC group (n = 5). Scale bar = 1 cm. f The tumor volumes were detected at the indicated time. g The tumor weights were measured at the termination of the experiment. h The expression of NEAT1 in tumor tissues was detected by qRT-PCR. All of the data are shown as the means ± SD. ^*P < 0.05; ^**P < 0.01