CircRNA PIP5K1A promotes the progression of glioma through upregulation of the TCF12/PI3K/AKT pathway by sponging miR-515-5p

Table 1 Relationship between the CircPIP5K1A level and clinical characteristics in tissue samples from glioma patients

Characteristics	Patients	Expression of CircPIP5K1A		P-value
Characteristics	Patients	Low-CircPIP5K1A	High-CircPIP5K1A	P-value
Total	45	20	25
Age (years)
<45	20	8	12	0.592
≥45	25	12	13	0.592
Gender
Male	24	11	13	0.841
Female	21	9	12	0.841
IDH1 mutation
No mutation	24	10	14	0.8241
Mutation	19	9	11	0.8241
MGMT promoter methylation
Unmethylation	26	13	12	0.5549
Methylation	23	10	13	0.5549
Tumor stage (WHO)
I-II	27	11	16	0.014*
III-IV	18	4	14	0.014*
Ki-67 rate level
Low	19	13	6	0.0057*
High	26	7	19	0.0057*
Tumor volume
<5 cm	28	15	11	0.036*
≥5 cm	17	5	14	0.036*

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