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Table 3 XPF expression in CRC, adenoma and anal benign disease tissue

From: XPF expression and its relationship with the risk and prognosis of colorectal cancer

Category

Group

Cases

(−)

(+)

(++)

(+++)

PR (%)

P

n (%)

n (%)

n (%)

n (%)

Overall

CRC

276

131

116

17

12

52.5%

<0.001

Adenoma

202

116

67

15

4

42.6%

Anal disease

62

55

6

1

0

11.3%

Male

CRC

143

66

62

9

6

53.8%

<0.001

Adenoma

24

19

4

0

1

20.8%

Anal disease

19

17

1

1

0

10.5%

Female

CRC

105

58

39

6

2

44.8%

0.001

Adenoma

26

16

6

2

2

38.5%

Anal disease

42

37

5

0

0

11.9%

≤60

CRC

119

62

47

7

3

47.9%

0.001

Adenoma

26

18

6

1

1

30.8%

Anal disease

38

32

5

1

0

15.8%

>60

CRC

129

62

54

8

5

51.9%

<0.001

Adenoma

24

17

4

1

2

29.2%

Anal disease

22

21

1

0

0

4.5%

Colon

CRC

82

54

21

3

4

34.1%

0.275

Adenoma

10

8

2

0

0

20.0%

Rectum

CRC

166

70

80

12

4

57.8%

0.109

Adenoma

33

22

6

2

3

33.3%

  1. PR positive rate. Negative (−), light positive (+), positive (++), strong positive (+++) staining. Mann–Whitney U- test of nonparametric test to compare the XPF protein expression between CRC and adjacent tissue
  2. The italics values: P < 0.05