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Fig. 1 | Cancer Cell International

Fig. 1

From: CAFs affect the proliferation and treatment response of head and neck cancer spheroids during co-culturing in a unique in vitro model

Fig. 1

Ki67 expression in HNSCC cells grown in 3D ± CAFs. Immunohistochemical staining of untreated HNSCC tumor spheroids ± CAFs with the proliferation marker Ki67 cultured for 5 days: scale bar = 150 µm. Clusters with tumor cells are indicated with arrows. Quantification of Ki67-positive cells in 5 days old tumor spheroids; data are shown as Ki67 positive cells/area ± SD, 2 experiments, images = n ≥ 6. *p < 0.05 according to one-way ANOVA with Bonferroni adjustment

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