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Fig. 2 | Cancer Cell International

Fig. 2

From: CAFs affect the proliferation and treatment response of head and neck cancer spheroids during co-culturing in a unique in vitro model

Fig. 2

Ki67 expression in HNSCC cells grown in 3D ± CAFs after treatment with cisplatin and cetuximab. Proliferation in response to treatment with cetuximab and cisplatin was measured by immunohistochemical staining with the proliferation marker Ki67. Quantification of Ki67-positive cells in 5 days old tumor spheroids; data are depicted as Ki67 positive cells/area ± SD, 2 experiments, images = n ≥ 6. *p < 0.05 according to one-way ANOVA with Bonferroni adjustment

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