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Fig. 3 | Cancer Cell International

Fig. 3

From: TRAIL promotes hepatocellular carcinoma apoptosis and inhibits proliferation and migration via interacting with IER3

Fig. 3

TRAIL and IER3 suppress HCC cell survival, migration, and colony formation. a Huh7 cells were co-infected with Ad5-TRAIL and Ad5-IER3, after which viability was assessed via MTT assay. b A colony formation assay was employed to assess the viability of cells prepared as in a. c The impact of TRAIL and IER3 synergistic effect on apoptotic cell death in Huh7 cells was evaluated via flow cytometry. d In a wound healing assay, adenoviral of TRAIL and IER3 synergistic effect was found to suppress Huh7 cell migration. e A Transwell assay was used to assess the migration of cells that had been infected with Ad5-TRAIL or/and Ad5-IER3. Data are means ± s.d. (*P < 0.05, **P < 0.01)

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Cancer Cell International

ISSN: 1475-2867

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