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Table 1 Correlation between IER3 expression and clinicopathologic characteristics of HCC patients

From: TRAIL promotes hepatocellular carcinoma apoptosis and inhibits proliferation and migration via interacting with IER3

Characteristics IER3

No. of cases (%)

IER3 expreesion

Low or none, no. cases

High, no. cases

Statistic (c2)

p value

Age

  < 50

37 (41.1)

14

23

1.509

0.219

  ≥ 50

53 (58.9)

27

26

Gender

 Male

80 (88.9)

37

43

0.14

0.708

 Female

10 (11.1)

4

6

HBsAg

 Positive

70 (77.8)

29

41

2.84

0.092

 Negative

19 (21.1)

12

7

HBcAb

 Positive

80 (88.9)

35

45

1.985

0.159

 Negative

7 (7.8)

5

2

HCV

 Positive

1 (1.1)

0

1

0.861

0.353

 Negative

86 (95.6)

40

46

Liver cirrhosis

 Yes

80 (88.9)

38

42

0.09

0.419

 No

9 (10.0)

3

6

Total bilirubin (mmol/L)

  < 21

75 (83.3)

36

39

0.717

0.397

  ≥ 21

14 (15.6)

5

9

ALT (U/L)

     

  < 60

70 (77.8)

29

41

2.84

0.092

  ≥ 60

19 (21.1)

12

7

GGT (U/L)

  < 40

30 (33.3)

9

21

4.702

0.030

  ≥ 40

59 (65.6)

32

27

AFP (ng/L)

  < 20

36 (40.0)

17

19

0.067

0.795

  ≥ 20

54 (60.0)

24

30

Cirrhotic nodules

 Single

10 (11.1)

5

5

0.653

0.765

 Multiple

80 (88.9)

36

44

Vascular invasion

 Yes

21 (23.3)

12

9

1.545

0.214

 No

58 (64.4)

24

34

Tumor number

 Single

79 (87.8)

36

43

0

0.994

 Multiple

11 (12.2)

5

6

Tumor size

  < 5 cm

55 (61.1)

16

39

15.458

 < 0.001

  ≥ 5 cm

35 (38.9)

25

10

Recrudescence

 Yes

49 (54.4)

27

22

3.952

0.047

 No

41 (45.6)

14

27

AJCC TNM stage

 I stage

58 (64.4)

24

34

1.392

0.499

 II stage

29 (32.2)

15

14

 III stage

3 (33.3)

2

1

  1. P values were calculated using chi-square test. Italics numbers indicate significant differences (P < 0.05)
  2. HCC hepatocellular carcinoma, HBsAg hepatitis B surface antigen, HBcAb hepatitis B core antigen, HCV hepatitis C virus, ALT alanine transaminase, GGT Gamma-Glutamyltransferase, AFP α-fetoprotein, AJCC the American Joint Committee on Cancer, TNM tumor-node-metastasis
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Cancer Cell International

ISSN: 1475-2867

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