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Fig. 3 | Cancer Cell International

Fig. 3

From: Ceramide kinase mediates intrinsic resistance and inferior response to chemotherapy in triple‐negative breast cancer by upregulating Ras/ERK and PI3K/Akt pathways

Fig. 3

CERK overexpression alleviates cytotoxicity of chemotherapeutic agents in TNBC cells. CERK overexpression alleviates the anti-proliferative (a) and pro-apoptotic (b) effects of paclitaxel and cisplatin in TNBC cells. Paclitaxel at 2 µM and cisplatin at 50 µM were used in proliferation and apoptosis assays. Proliferation and migration were measured after 72-h incubation; *P < 0.05, compared with pCMV3

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Cancer Cell International

ISSN: 1475-2867

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