From: Ceramide kinase mediates intrinsic resistance and inferior response to chemotherapy in triple‐negative breast cancer by upregulating Ras/ERK and PI3K/Akt pathways
CERK (tumor)/CERK (normal) in TNBC
TNBC (patients) (n = 100)
< 2% (n)
> 2% (n)
Resistance
43% (20)
75% (40)
OR = 2.66
95% CI (1.18–7.34)
P = 0.04
Sensitive
57% (27)
25% (13)