Fig. 2

Depletion of miR-17-5p inhibits cell proliferation and promotes cell apoptosis in LSCC in vitro. a Hep2 cells and SCC-2 cells were transfected with miR-17-5p inhibitor or inhibitor-NC. miR-17-5p expression was detected by using qRT-PCR. ***P < 0.001 vs. inhibitor-NC. b Cells were treated as (a), cell viability was measured by using CCK-8 assay in different times. Data shown are mean ± standard deviation of three independent experiments. *P < 0.05, **P < 0.01, ***P < 0.001 vs. inhibitor-NC. c Cells were treated as (a) for 48 h. Cell apoptosis was assessed by Annexin V-FITC/PI staining. Right panel shows the apoptosis rate of three independent experiments. **P < 0.01, ***P < 0.001 vs. inhibitor-NC