Fig. 2

LPAR3 and EGFR mediate TC progression. a The interference efficiency of shRNAs specifically targeting to LPAR3 and EGFR (sh-LPAR3#1/2 and sh-EGFR#1/2) were validated by qRT-PCR. Sh-NC was a negative control. b, c The proliferation of transfected cells was analyzed through CCK-8 and colony formation assays. d, e Flow cytometry and TUNEL analyses were applied to determine the apoptotic rate of TPC-1 and BCPAP cells after transfection. **P < 0.01