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Fig. 1 | Cancer Cell International

Fig. 1

From: SP1 induced long non-coding RNA LINC00958 overexpression facilitate cell proliferation, migration and invasion in lung adenocarcinoma via mediating miR-625-5p/CPSF7 axis

Fig. 1

LINC00958 is predominantly up-regulated in LAD and silencing LINC00958 suppresses LAD cell proliferation, migration and invasion. a QRT-PCR analysis was used to determine the expression status of LINC00958 in LAD cell lines and normal pulmonic cell line (HBE). b The inhibitory efficiency of sh-LINC00958#1/2 was detected by qRT-PCR analysis. c, d Colony formation and EdU assays were performed to determine the proliferation ability of transfected cells. e TUNEL assay was used to evaluate cell apoptosis in different groups. f, g Transwell migration and invasion assays were conducted to assess the abilities of transfected cells to migrate and invade. h Western blot assay was performed to measure EMT-related protein expression level change in different groups. **P < 0.01

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Cancer Cell International

ISSN: 1475-2867

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