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Fig. 2 | Cancer Cell International

Fig. 2

From: EphA5 knockdown enhances the invasion and migration ability of esophageal squamous cell carcinoma via epithelial-mesenchymal transition through activating Wnt/β-catenin pathway

Fig. 2

Knockdown of EphA5 promoted the proliferation, migration, and invasion of ESCC cells in vitro. a Western blotting and qRT-PCR results showed that EphA5 expression in KYSE150 and KYSE450 cells was downregulated by siRNA treatment. b The proliferation rate of the si-EphA5 groups was higher than that of the NC groups in KYSE150 and KYSE450 cells. c The colonies formed by cells treated with si-EphA5 was more than that of NC groups in KYSE150 and KYSE450 cells. d EphA5 knockdown significantly promoted the invasion of KYSE150 and KYSE450 cells compared with the NC groups. e Wound-healing assay showed knockdown of EphA5 enhanced cell migration in KYSE150 at 12 h and KYSE450 cells at 48 h. *P < 0.05, **P < 0.01, ***P < 0.001 versus NC group

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Cancer Cell International

ISSN: 1475-2867

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