EphA5 knockdown enhances the invasion and migration ability of esophageal squamous cell carcinoma via epithelial-mesenchymal transition through activating Wnt/β-catenin pathway

Table 1 Association of EPHA5 expression with clinicopathological features in ESCC patients

Characteristic	Patients with FFPE	EPHA5 expression		χ²	P value^a
Characteristic	Tissue (n = 48)	Negative + low	High	χ²	P value^a
Age				0.844	0.358
≤ 65	23	20	3
> 65	25	18	7
Sex				0	1
Male	34	27	7
Female	14	11	3
Histologic grade				0.448	0.503
Grade I–II	37	28	9
Grade III	11	10	1
TNM stage				0.034	0.854
I-II	18	15	3
III-IVA	30	23	7
Lymph node status				3.158	0.076
Negative	24	22	2
Positive	24	16	8
Vascular or nerve invasion				0	1
Negative	34	27	7
Positive	14	11	3

Lymph node status: negative, no positive nodal metastases; positive, number of positive nodal metastases ≥ 1
FFPE, formalin fixed paraffin-embedded
^aPearson’s χ² test

ISSN: 1475-2867