Fig. 5

CircPIP5K1A facilitates GC progression by targeting miR-376c-3p/ZNF146 axis. a The overexpression efficiency of ZNF146 in MKN-45 cells was detected by RT-qPCR. b–d CCK-8, colony formation and EdU analyses were applied to measure the proliferative ability of MKN-45 cells transfected with different plasmids. e Transwell assay analyzed the capability of cell migration and invasion in different groups. f–g TUNEL and flow cytometry assays were used to evaluate the apoptosis rate of transfected cells. ^*P < 0.05, ^**P < 0.01