Fig. 1
From: The multifaceted roles of long noncoding RNAs in pancreatic cancer: an update on what we know
Current understanding of the lncRNA mechanisms involved in PDAC. a LncRNAs can function together with transcription factors to regulate target genes. b LncRNAs can guide and recruit chromatin-modifying enzymes to target genes. c LncRNAs interact with transcription factors or other protein factors to regulate transcription initiation. d LncRNAs aggregate a variety of proteins to form a rib nucleoprotein complex that affects histone modifications. e LncRNAs sponge functional miRNAs. f LncRNAs recruit effector molecules as adaptors to form protein complexes