Cancer Cell International

Table 2 Correlation between the clinicopathological characteristics and BRD4 and CAV-2 expression in PC

From: Caveolin-2 is regulated by BRD4 and contributes to cell growth in pancreatic cancer

Characteristics	N	BRD4 level		p-value	CAV-2 level		p-value
Characteristics	N	Low (26)	High (50)	p-value	Low (34)	High (42)	p-value
Age (years)
≤ 60	23	5	18	0.131	8	15	0.250
> 60	53	21	32		26	27	0.250
Gender
Male	49	18	31	0.532	22	27	0.970
Female	27	8	19		12	15	0.970
Clinical stage
Early stages (≤ I)	12	8	4	0.024*	11	1	< 0.001*
Advanced stages (> I)	64	18	46		23	41	< 0.001*
Invasion depth
T1 + T2	17	8	9	0.205	12	5	0.015*
T3 + T4	59	18	41		22	37	0.015*
Lymph nodes metastasis
N0 (negative)	33	16	17	0.022*	21	12	0.004*
N1 (positive)	43	10	33		13	30	0.004*
Distant metastasis
M0 (absent)	72	25	47	1.000	33	39	0.765
M1 (present)	4	1	3		1	3	0.765
Tumor differentiation
Well, moderate	51	19	32	0.424	27	24	0.040*
Poor	25	7	18		7	18	0.040*
Tumor location
Head, neck	39	10	29	0.106	14	25	0.112
Body, tail	37	16	21		20	17	0.112
Nervous invasion
Negative	25	13	12	0.022*	14	11	0.167
Positive	51	13	38		20	31	0.167
Vessel invasion
Negative	65	26	39	0.025*	32	33	0.112
Positive	11	0	11		2	9	0.112

Asterisk represents the significant difference

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ISSN: 1475-2867

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