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Table 1 Main characteristics of the studies selected for the meta-analysis

From: Integrated characterization and validation of the prognostic significance of microRNA-200s in colorectal cancer

First authorYearCountryEthnicityM/FNAgeTNM stagemiRNASample souceMethodsEndpointsMedian follow-up timeHazard ratio
Xi2006GermanyEuropeans10/142462I–IVmiR-200cTissueRT–PCROS400.68 (0.51–0.92)
Toiyama2014JapanAsians105/7718267I–IVmiR-200cBloodRT–PCROS500.37 (0.18–0.78)
Toiyama2014JapanAsians89/6715668I–IVmiR-200cTissueRT–PCROS501.79 (0.91–3.57)
Pichler2014USAAmericans71/4011160II–IVmiR-200aTissueRT–PCROS382.04 (1.28–3.25)
Diaz2014SpainEuropeans69/5812767I–IIImiR-200aTissueRT-PCROS1131.20 (1.03–1.40)
Diaz2014SpainEuropeans69/5812767I–IIImiR-200cTissueRT-PCROS1131.12 (1.01–1.25)
Maierthaler2016GermanyEuropeans162/14630870I–IIImiR-200aBloodRT-PCROS720.95 (0.71–1.26)
Maierthaler2016GermanyEuropeans162/14630870I–IIImiR-200bBloodRT-PCROS721.29 (0.96–1.75)
Maierthaler2016GermanyEuropeans162/14630870I–IIImiR-200cBloodRT-PCROS721.19 (0.93–1.52)
Maierthaler2016GermanyEuropeans130/8921968IVmiR-200aBloodRT-PCROS720.81 (0.67–0.99)
Maierthaler2016GermanyEuropeans130/8921968IVmiR-200bBloodRT-PCROS720.83 (0.67–1.03)
Maierthaler2016GermanyEuropeans130/8921968IVmiR-200cBloodRT-PCROS720.87 (0.73–1.03)
Sun2016USAAmericans22/254754I–IVmiR-200bBloodRT-PCROS280.38 (0.19–0.77)
Slattery2016USAAmericans401/34474564I–IVmiR-200aTissueRT-PCROS501.12 (0.95–1.33)
Slattery2016USAAmericans401/34474564I–IVmiR-200aTissueRT-PCROS501.01 (0.93–1.10)
Slattery2016USAAmericans401/34474564I–IVmiR-200bTissueRT-PCROS501.11 (0.95–1.30)
Slattery2016USAAmericans401/34474564I–IVmiR-200bTissueRT-PCROS501.01 (0.90–1.14)
Slattery2016USAAmericans401/34474564I–IVmiR-200cTissueRT-PCROS501.08 (0.90–1.28)
Slattery2016USAAmericans213/18339664I–IVmiR-200aTissueRT-PCROS501.18 (0.97–1.41)
Slattery2016USAAmericans213/18339664I–IVmiR-200aTissueRT-PCROS501.10 (1.01–1.20)
Slattery2016USAAmericans213/18339664I–IVmiR-200bTissueRT-PCROS501.41 (1.05–1.89)
Slattery2016USAAmericans213/18339664I–IVmiR-200bTissueRT-PCROS501.09 (0.92–1.28)
Slattery2016USAAmericans213/18339664I–IVmiR-200cTissueRT-PCROS501.28 (0.96–1.72)
Roh2018South KoreaAsians67/4210968I–IVmiR-200cTissueRT-PCROS350.45 (0.16–1.27)
Shelton2018USAAmericansNA106NAI–IVmiR-200aTissueRT-PCROS1202.27 (1.27–4.35)
Shelton2018USAAmericansNA108NAI–IVmiR-200bTissueRT-PCROS1202.17 (1.35–3.57)
Santasusagna2018SpainEuropeans31/195072I–IIImiR-200cBloodRT-PCROS450.81 (0.67–0.99)
Carter2019USAAmericans112/8719966I–IVmiR-200aTissueRT-PCROS962.01(1.09–3.72)
Carter2019USAAmericans112/8719966I–IVmiR-200bTissueRT-PCROS961.80 (0.98–3.31)
Carter2019USAAmericans112/8719966I–IVmiR-200cTissueRT-PCROS961.97(1.08–3.62)
  1. F female, M male, N number, OS overall survival