Fig. 6

Upregulation of hsa_circ_0137008 attenuated the effect of miR-338-5p on CRC cell migration, invasion, and EMT. SW480 and HCT116 cells were transfected with miR-NC, miR-338-5p mimic alone or with pcDNA3.1-circ_0137008. a The migration ability of SW480 and HCT116 cells was examined using wound healing assay. b The invasion ability of SW480 and HCT116 cells was examined using transwell invasion assay. c The expression of E-cadherin, vimentin and N-cadherin was detected using western blot. d–f Results of quantitative analysis of the E-cadherin, vimentin and N-cadherin protein levels were shown. *P < 0.05