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Fig. 2 | Cancer Cell International

Fig. 2

From: YY1-induced lncRNA ZFPM2-AS1 facilitates cell proliferation and invasion in small cell lung cancer via upregulating of TRAF4

Fig. 2

ZFPM2-AS1 was transcriptionally activated by YY1. a YY1 binding motif and the related binding site for YY1 in ZFPM2-AS1 promoter were acquired via searching JASPAR. b, c qRT-PCR and western blot analyses of YY1 mRNA level upon YY1 elevation or suppression. d The expression of ZFPM2-AS1 in response to YY1 elevation or suppression was detected by qRT-PCR. e The binding relation between YY1 and ZFPM2-AS1 promoter was ensured by ChIP using anti-YY1. f, g The luciferase activity of wild ZFPM2-AS1 promoter (P1) in differently transfected groups was detected by luciferase reporter assay. *P < 0.05, **P < 0.01. NS: no significance

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Cancer Cell International

ISSN: 1475-2867

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