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Fig. 2 | Cancer Cell International

Fig. 2

From: M2 bone marrow-derived macrophage-derived exosomes shuffle microRNA-21 to accelerate immune escape of glioma by modulating PEG3

Fig. 2

Depleting miR-21 suppresses growth, migration and invasion as well as accelerates apoptosis of glioma cells. a Cell proliferation tested by EdU assay. b Detection of apoptosis by flow cytometry. c Cell invasion tested by Transwell assay. d Cell migration detected by scratch test. e The protein expression of Bcl-2, Bax, MMP-2 and MMP-9 measured by western blot assay. N = 3. *p < 0.05 vs. the inhibitors NC group. The measurement data were represented by mean ± standard deviation. Comparison between two groups were assessed by t test

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