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Fig. 5 | Cancer Cell International

Fig. 5

From: M2 bone marrow-derived macrophage-derived exosomes shuffle microRNA-21 to accelerate immune escape of glioma by modulating PEG3

Fig. 5

Identification of M2 BMDM and its exosomes. a Morphology of macrophages without IL-4 and IL-13 polarization (scale bar: 25 μm). b Morphology of macrophages stimulated by IL-4 and IL-13 polarization (scale bar: 25 μm). c Expression of Arg-1 and CD163 proteins in polarized and un-polarized-stimulated macrophages. d BMDM-Exos morphology under transmission electron microscope (scale bar: 100 nm). e Expression of exosomes marker proteins TSG101, CD63 and CD81. F, Exosomes uptake test (scale bar: 25 μm)

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