Fig. 8
From: MiR-26a/miR-26b represses tongue squamous cell carcinoma progression by targeting PAK1
Upregulated PAK1 attenuated inhibition of glycolysis caused by miR-26a and miR-26b in TSCC cells. SCC4 and Cal27 cells were transfected with miR-NC, miR-26a/miR-26b mimic, miR-26a/miR-26b mimic + pcDNA Vector or miR-26a/miR-26b mimic + pcDNA-PAK1. a–d Analysis for the glucose consumption of treated SCC4 and Cal27 was assessed by commercial kits, as determined by ANOVA analysis followed by Tukey test. e–h Analysis for the lactate production in transfected SCC4 and Cal27 was evaluated, as determined by ANOVA analysis followed by Tukey test. *P < 0.05, **P < 0.01, ***P < 0.001