Fig. 3

Circ_0007534 targeted miR-206 in CC cells. a Starbase showed the binding sites between circ_0007534 and miR-206. b, c The interaction between circ_0007534 and miR-206 was confirmed by dual-luciferase reporter assay in SiHa (b) and HeLa (c) cells. d, e The qRT-PCR identified the downregulation of miR-206 expression in CC tissues d by comparison with normal tissues and CC cells (e) by comparison with normal cells. f The qRT-PCR indicated that miR-206 level was elevated after knockdown of circ_0007534. WT wild-type, MUT mutant-type, CC cervical cancer, NC negative control. All assays were performed for three times with technical n = 3. Statistical analysis was conducted by Student’s t-test and one-way analysis of variance followed by Tukey’s test. *P < 0.05, **P < 0.01