Fig. 6
From: Postponing tumor onset and tumor progression can be achieved by alteration of local tumor immunity
IL-6 suppresses the maturation of dendritic cells in Fvb mice, and the VEGF level is decreased in Fvb.B6 mice. a Level of serum IL-6 and VEGF in Fvb.B6 (n = 5) and Fvb (n = 5) mice was detected by a Mcytomag-70 K-32 Mouse Cytokine/Chemokine Magnetic Bead Panel. b IHC staining of IL-6 in breast cancer tissues from Fvb.B6 (n = 10) and Fvb (n = 10) mice at adenoma. c Experimental strategy and BMDCs were induced from day 6 to day 8, with or without 10 ng/mL of mouse IL-6 treatment on day 6. d, e Plots depicting CD80 (d) and CD86 (e) expression by BMDCs after 2 days of coculturing with or without IL-6. f CD80 and CD86 expression by BMDCs (n = 5) with means ± SEM shown