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Fig. 4 | Cancer Cell International

Fig. 4

From: IRF4 overexpression promotes the transdifferentiation of tregs into macrophage‐like cells to inhibit the development of colon cancer

Fig. 4

IRF4 overexpression promoted the transdifferentiation of Tregs into macrophage-like cells. Tregs were transfected with LV-IRF4 or LV-ctrl. Normal Tregs served as control. QRT-PCR (a) and WB ( b) were performed to assess the gene and protein expression of IRF4 in the modified Tregs. c The proportions of macrophages in the modified Tregs were detected by flow cytometry. d The phagocytosis assay was performed to assess the phagocytosis of the modified Tregs. The phagocytosis positive cells were marked by arrows. (**P < 0.01, versus LV-ctrl)

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Cancer Cell International

ISSN: 1475-2867

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