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Fig. 9 | Cancer Cell International

Fig. 9

From: IRF4 overexpression promotes the transdifferentiation of tregs into macrophage‐like cells to inhibit the development of colon cancer

Fig. 9

IRF4 was the target of miR-27a-3p, miR-30a-5p and miR-320c, respectively. a The Wt (Mut) 3′UTR of IRF4 vector and miR-27a-3p mimic or mimic NC were co-transfected into 293 cells. The interaction between miR-27a-3p and IRF4 was measured by luciferase reporter assay. b The Wt (Mut) 3′UTR of IRF4 vector and miR-30a-5p mimic or mimic NC were co-transfected into 293 cells. The interaction between miR-30a-5p and IRF4 was measured by luciferase reporter assay. c The Wt (Mut) 3′UTR of IRF4 vector and miR-320c mimic or mimic NC were co-transfected into 293 cells. The interaction between miR-320c and IRF4 was measured by luciferase reporter assay. (**P < 0.01, versus mimic NC)

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