Fig. 1
From: LncRNA ACTA2-AS1 suppress colon adenocarcinoma progression by sponging miR-4428 upregulation BCL2L11
LncRNA ACTA2-AS1 was down-expression in COAD tissue samples and cells. a ACTA2-AS1 was down-expressed in COAD samples from TCGA database. b Relative ACTA2-AS1 expression in 82 pairs of COAD tissue samples and their adjacent normal tissues using qRT-PCR assay. c Relative ACTA2-AS1 expression in different COAD cell lines (SW480, HT29, LS174T, HCT116 and DLD-1) and normal human colon mucosal epithelial cell line CCD-18Co. d Relative ACTA2-AS1 expression in different clinical stages of COAD. e Downregulation of ACTA2-AS1 in COAD was associated with lymph node metastasis. f Downregulation of ACTA2-AS1 in COAD was associated with distant metastasis. g The KM-Plotter was used to evaluate survival in COAD patients. Patients with low ACTA2-AS1 expression had worse overall survival than those with high ACTA2-AS1 expression. h Localization of ACTA2-AS1 in COAD cells using nuclear cytoplasm separation experiment. *p < 0.05; **p < 0.01