Fig. 1

CFL-1, LIMK1, and SSH1 mRNA levels and prognostic value analysis in CRC tissues according to RNA-Seq data from TCGA Data Bank. a Expression of CFL-1, LIMK1, and SSH1 in normal colon tissues (n = 51) and according to tumor stage of CRC (n = 599). Kaplan–Meier curves depicting the overall survival (5 years) was generated based on the LIMK1 expression in CRC tissues using TCGA Data Bank. The log-rank test was used to analyze differences in survival curves between the groups. Samples expressing the gene above or equal the median were classified as high expression and the others as low expression. LIMK1 expression was evaluated in b all tumor stages I–IV (high n = 266; low n = 264), c early stage I–II (high n = 174; low n = 173), d late stage III–IV (high n = 137; low n = 136)