Table 2 Association between CFL-1 IHC score and clinicopathological features of CRC patients
Features | n | CFL-1 IHC score, n (%) | χ2 value | P-valuea | |
|---|---|---|---|---|---|
Low | High | ||||
Gender | |||||
Male | 23 | 10(43.4) | 13(56.6) | 0.208 | 0.648 |
Female | 26 | 13(50) | 13(50) | ||
Age at surgery (years) | |||||
≥ 65 | 27 | 11(40.7) | 16(59.3) | 0.927 | 0.335 |
< 65 | 22 | 12(54.5) | 10(45.5) | ||
Localization | |||||
Colon ascendens | 14 | 3(21.4) | 11(78.6) | 6.381 | 0.09 |
Colon descendens | 10 | 5(50) | 5(50) | ||
Colon transversum | 3 | 1(33.3) | 2(66.7) | ||
Colon sigmoideum/rectum | 22 | 14(63.6) | 8(36.4) | ||
Tumor type | |||||
Adenocarcinoma | 40 | 20(50) | 20(50) | 0.819 | 0.364 |
Adenocarcinoma/mucinous | 9 | 3(33.3) | 6(66.7) | ||
Tumor grade | |||||
Well differentiated | 1 | 1 (100) | 0 | 1.355 | 0.508 |
Moderately differentiated | 45 | 21(46.6) | 24(53.4) | ||
Poorly differentiated | 3 | 1(33.3) | 2(66.7) | ||
T stage (AJCC) | |||||
T1/2 | 15 | 10(66.7) | 5(33.3) | 7.985 | 0.001** |
T3 | 16 | 3(18.7) | 13(81.3) | ||
T4 | 18 | 10(55.5) | 8(44.5) | ||
Lymph node metastasis | |||||
Present | 19 | 5(26.3) | 14(73.7) | 5.299 | 0.02* |
Absent | 30 | 18(60) | 12(40) | ||
Liver metastasis | |||||
Present | 13 | 7(53.8) | 6(46.2) | 0.339 | 0.560 |
Absent | 36 | 16(44.4) | 20(55.6) | ||
Lymphovascular invasion | |||||
Present | 13 | 7(53.8) | 6(46.2) | 0.339 | 0.560 |
Absent | 36 | 16(44.4) | 20(55.6) | ||
Perineural invasion | |||||
Present | 11 | 6(54.5) | 5(45.6) | 0.329 | 0.565 |
Absent | 38 | 17(44.7) | 21(55.3) | ||
Tumor size (cm3 ) | |||||
≥ 33 | 24 | 10(41.7) | 14(58.3) | 0.525 | 0.468 |
< 33 | 25 | 13(52) | 12(48) | ||