Table 3 Association between SSH1 IHC score and clinicopathological features of CRC patients
Features | n | SSH1 IHC Score, n (%) | χ2 value | P-valuea | |
|---|---|---|---|---|---|
Low | High | ||||
Gender | |||||
Male | 23 | 9(39.1) | 14(60.9) | 1.061 | 0.303 |
Female | 26 | 14(53.8) | 12(46.2) | ||
Age at surgery (years) | |||||
≥ 65 | 27 | 14(51.8) | 13(48.2) | 0.582 | 0.442 |
< 65 | 22 | 9(40.9) | 13(59.1) | ||
Localization | |||||
Colon ascendens | 14 | 6(42.8) | 8(57.2) | 2.773 | 0.428 |
Colon descendens | 10 | 7(70) | 3(30) | ||
Colon transversum | 3 | 1(33.3) | 2(66.7) | ||
Colon sigmoideum/rectum | 22 | 9(40.9) | 13(59.1) | ||
Tumor type | |||||
Adenocarcinoma | 40 | 20(50) | 20(50) | 0.819 | 0.364 |
Adenocarcinoma/mucinous | 9 | 3(33.3) | 6(66.7) | ||
Tumor grade | |||||
Well differentiated | 1 | 1(100) | 0 | 1.355 | 0.508 |
Moderately differentiated | 45 | 21(46.6) | 24(53.4) | ||
Poorly differentiated | 3 | 1(33.3) | 2(66.7) | ||
T stage (AJCC) | |||||
T1/2 | 15 | 8(53.3) | 7(46.7) | 2.364 | 0.306 |
T3 | 16 | 5(31.3) | 11(68.7) | ||
T4 | 18 | 10(55.5) | 8(44.5) | ||
Lymph node metastasis | |||||
Present | 19 | 5(26.3) | 14(73.7) | 5.299 | 0.02* |
Absent | 30 | 18(60) | 12(40) | ||
Liver metastasis | |||||
Present | 13 | 7(53.8) | 6(46.2) | 0.339 | 0.560 |
Absent | 36 | 16(44.4) | 20(55.6) | ||
Lymphovascular invasion | |||||
Present | 13 | 6(46.1) | 7(53.9) | 0.004 | 0.947 |
Absent | 36 | 17(47.3) | 19(52.7) | ||
Perineural invasion | |||||
Present | 11 | 5(45.5) | 6(54.5) | 0.125 | 0.910 |
Absent | 38 | 18(47.4) | 20(52.6) | ||
Tumor size (cm3) | |||||
≥ 33 | 24 | 12(50) | 12(50) | 0.177 | 0.674 |
< 33 | 25 | 11(44) | 14(56) | ||