Table 4 Association between LIMK1 IHC score and clinicopathological features of CRC patients
Features | n | LIMK1 IHC score, n (%) | χ2 value | P-valuea | |
|---|---|---|---|---|---|
Low | High | ||||
Gender | |||||
Male | 23 | 11(47.8) | 12(52.2) | 0.023 | 0.879 |
Female | 26 | 13(50) | 13(50) | ||
Age at surgery (years) | |||||
≥ 65 | 27 | 13(48.1) | 14(51.9) | 0.016 | 0.897 |
< 65 | 22 | 11(50) | 11(50) | ||
Localization | |||||
Colon ascendens | 14 | 5(35.7) | 9(64.3) | 5.761 | 0.123 |
Colon descendens | 10 | 5(50) | 5(50) | ||
Colon transversum | 3 | 0 | 3(100) | ||
Colon sigmoideum/rectum | 22 | 14(63.6) | 8(36.4) | ||
Tumor type | |||||
Adenocarcinoma | 40 | 21(52.5) | 19(47.5) | 1.080 | 0.298 |
Adenocarcinoma/mucinous | 9 | 3(33.3) | 6(66.7) | ||
Tumor grade | |||||
Well differentiated | 1 | 1(100) | 0 | 4.003 | 0.135 |
Moderately differentiated | 45 | 23(51.1) | 22(48.9) | ||
Poorly differentiated | 3 | 0 | 3(100) | ||
T stage (AJCC) | |||||
T1/2 | 15 | 7(46.7) | 8(53.3) | 0.046 | 0.977 |
T3 | 16 | 8(50) | 8(50) | ||
T4 | 18 | 9(50) | 9(50) | ||
Lymph node metastasis | 0.032 | 0.857 | |||
Present | 19 | 9(47.4) | 10(52.6) | ||
Absent | 30 | 15(50) | 15(50) | ||
Liver metastasis | |||||
Present | 13 | 7(53.9) | 6(46.1) | 0.167 | 0.682 |
Absent | 36 | 17(47.2) | 19(52.8) | ||
Lymphovascular invasion | |||||
Present | 13 | 6(46.1) | 7(53.9) | 0.056 | 0.812 |
Absent | 36 | 18(50) | 18(50) | ||
Perineural invasion | |||||
Present | 11 | 6(54.5) | 5(45.5) | 0.012 | 0.910 |
Absent | 38 | 20(52.6) | 18(47.4) | ||
Tumor size (cm3) | |||||
≥ 33 | 24 | 13(54.1) | 11(45.9) | 0.506 | 0.476 |
< 33 | 25 | 11(44) | 14(56) | ||