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Fig. 5 | Cancer Cell International

Fig. 5

From: LncRNA MEG8 promotes NSCLC progression by modulating the miR-15a-5p-miR-15b-5p/PSAT1 axis

Fig. 5

LncRNA MEG8 promotes NSCLC cell proliferation, migration, and invasion by targeting miR-15a/b-5p in vitro. ac The A549 and H1299 cells were treated with control shRNA (Ctrl), MEG8 shRNA (shMEG8), miR-15a/b-5p inhibitors, or co-treated with MEG8 shRNA (shMEG8) and the inhibitors of miR-15a/b-5p, respectively. a Cell viability was measured by CCK-8 assays in the cells. b, c The cell apoptosis was measure by flow cytometry analysis in the cells, in which the x-axis represented the Annexin V-FITC and the y-axis represented the propidium iodide (PI). Data are presented as mean ± SD. Statistic significant differences were indicated: *P < 0.05, **P < 0.01, #P < 0.05

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