Fig. 6

LiCl inhibits choroidal melanoma cell tumorigenesis in vivo. a The mouse experiments were performed once. BALB/c nude male mice were randomly divided into a LiCl group and a normal saline group, with 5 mice per group. M619 cells (3 × 10⁶ cells in 100 μl of PBS) were subcutaneously injected into the right flank region of each nude mouse, and then tumours were grown in the mice. The LiCl group was treated with LiCl (141.3 mg/kg; i.p., daily), and the normal saline group received an equal volume of normal saline for 2 weeks. b, c At 15 days after inoculation, xenograft tumours were recovered and weighed. d The tumour volume was recorded every 3 days beginning on the day at which the tumours were first visible after injection. *P < 0.05. NS not significant