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Table 1 Population, intervention, comparison and outcomes (PICO) of the proposed question:

From: The effects of several postoperative adjuvant therapies for hepatocellular carcinoma patients with microvascular invasion after curative resection: a systematic review and meta-analysis

 

Interventions to treat HCC patients with microvascular invasion

Population

HCC patients diagnosed with MVI by pathology after curative resection and Child class A or B without macrovascular invasion and metastatic disease

Intervention vs Comparison

TACE versus conservation therapy; pa-TACE versus re-resection/ radiofrequency ablation ablation; pa-TACE versus radiotherapy; sorafenib versus conservation therapy

Outcomes

OS and/or RFS

Study design

Retrospective study (PSM or not) and randomized clinical trial

  1. Pa-TACE postoperative adjuvant transarterial chemoembolization
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Cancer Cell International

ISSN: 1475-2867

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