Fig. 4

Development of the prognostic signature based on 7 IRGs in the training set. a Overall survival (OS) of HCC patients in high- and low-risk groups. b Time- ROC curve of the 7-IRG prognostic signature. c The concordance index (C-index) of the clinical variates versus 7-IRG signature to evaluate prognostic accuracy for OS prediction. d Risk score distribution, e survival status, and f heatmap of expression profiles in high- and low-risk groups. *p < 0.05; ** p < 0.01; *** p < 0.001; ns, not significant