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Table 1 Clinical characteristics of 1013 glioma patients in the CGGA dataset according to FCER1G expression levels

From: Prognostic and predictive value of FCER1G in glioma outcomes and response to immunotherapy

FCER1G expression High Low P value
n 506 507  
FCER1G_mRNA (median [IQR]) 6.74 [6.22, 7.42] 4.69 [3.81, 5.22] < 0.001
Age (median [IQR]) 44.00 [36.00, 54.00] 41.00 [34.00, 49.00] 0.002
Gender (%)    0.371
 Female 199 (39.3) 214 (42.2)  
 Male 307 (60.7) 293 (57.8)  
Grade (%)    < 0.001
 II 101 (20.0) 187 (36.9)  
 III 140 (27.7) 193 (38.1)  
 IV 261 (51.6) 126 (24.9)  
  4 ( 0.8) 1 ( 0.2)  
Histology (%)    
 Anaplastic Astrocytoma 118 (23.3) 95 (18.7)  
 Anaplastic Oligoastrocytoma 2 ( 0.4) 19 ( 3.7)  
 Anaplastic Oligodendroglioma 19 ( 3.8) 75 (14.8)  
 Astrocytoma 81 (16.0) 92 (18.1)  
 GBM 261 (51.6) 126 (24.9)  
 Oligoastrocytoma 2 ( 0.4) 7 ( 1.4)  
 Oligodendroglioma 19 ( 3.8) 92 (18.1)  
  4 ( 0.8) 1 ( 0.2)  
Recurrence (%)    0.001
 Primary 296 (58.5) 350 (69.0)  
 Recurrent 186 (36.8) 147 (29.0)  
 Secondary 20 ( 4.0) 10 ( 2.0)  
  4 ( 0.8) 0 ( 0.0)  
Subtype (%)    < 0.001
 Classical 110 (21.7) 52 (10.3)  
 Mesenchymal 95 (18.8) 19 ( 3.7)  
 Proneural 82 (16.2) 74 (14.6)  
  219 (43.3) 362 (71.4)  
survival (median [IQR]) 17.50 [8.80, 40.60] 37.00 [15.35, 75.85] < 0.001
status (%)    
 Alive 125 (25.3) 260 (53.1) < 0.001
 Dead 369 (74.7) 230 (46.9)  
IDH status (%)    < 0.001
 Mutant 213 (42.1) 316 (62.3)  
 Wildtype 287 (56.7) 145 (28.6)  
  6 ( 1.2) 46 ( 9.1)  
1p19q (%)    < 0.001
 Codel 39 ( 7.7) 172 (33.9)  
 Non-codel 461 (91.1) 263 (51.9)  
  6 ( 1.2) 72 (14.2)  
Radio status (%) 68 (14.9) 94 (20.0) 0.047
 No    
 Yes 388 (85.1) 376 (80.0)  
Chemo status (%) 117 (26.1) 156 (34.2) 0.009
 No    
 Yes 332 (73.9) 300 (65.8)