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Table 1 Clinical characteristics of 1013 glioma patients in the CGGA dataset according to FCER1G expression levels

From: Prognostic and predictive value of FCER1G in glioma outcomes and response to immunotherapy

FCER1G expression

High

Low

P value

n

506

507

 

FCER1G_mRNA (median [IQR])

6.74 [6.22, 7.42]

4.69 [3.81, 5.22]

< 0.001

Age (median [IQR])

44.00 [36.00, 54.00]

41.00 [34.00, 49.00]

0.002

Gender (%)

  

0.371

 Female

199 (39.3)

214 (42.2)

 

 Male

307 (60.7)

293 (57.8)

 

Grade (%)

  

< 0.001

 II

101 (20.0)

187 (36.9)

 

 III

140 (27.7)

193 (38.1)

 

 IV

261 (51.6)

126 (24.9)

 
 

4 ( 0.8)

1 ( 0.2)

 

Histology (%)

   

 Anaplastic Astrocytoma

118 (23.3)

95 (18.7)

 

 Anaplastic Oligoastrocytoma

2 ( 0.4)

19 ( 3.7)

 

 Anaplastic Oligodendroglioma

19 ( 3.8)

75 (14.8)

 

 Astrocytoma

81 (16.0)

92 (18.1)

 

 GBM

261 (51.6)

126 (24.9)

 

 Oligoastrocytoma

2 ( 0.4)

7 ( 1.4)

 

 Oligodendroglioma

19 ( 3.8)

92 (18.1)

 
 

4 ( 0.8)

1 ( 0.2)

 

Recurrence (%)

  

0.001

 Primary

296 (58.5)

350 (69.0)

 

 Recurrent

186 (36.8)

147 (29.0)

 

 Secondary

20 ( 4.0)

10 ( 2.0)

 
 

4 ( 0.8)

0 ( 0.0)

 

Subtype (%)

  

< 0.001

 Classical

110 (21.7)

52 (10.3)

 

 Mesenchymal

95 (18.8)

19 ( 3.7)

 

 Proneural

82 (16.2)

74 (14.6)

 
 

219 (43.3)

362 (71.4)

 

survival (median [IQR])

17.50 [8.80, 40.60]

37.00 [15.35, 75.85]

< 0.001

status (%)

   

 Alive

125 (25.3)

260 (53.1)

< 0.001

 Dead

369 (74.7)

230 (46.9)

 

IDH status (%)

  

< 0.001

 Mutant

213 (42.1)

316 (62.3)

 

 Wildtype

287 (56.7)

145 (28.6)

 
 

6 ( 1.2)

46 ( 9.1)

 

1p19q (%)

  

< 0.001

 Codel

39 ( 7.7)

172 (33.9)

 

 Non-codel

461 (91.1)

263 (51.9)

 
 

6 ( 1.2)

72 (14.2)

 

Radio status (%)

68 (14.9)

94 (20.0)

0.047

 No

   

 Yes

388 (85.1)

376 (80.0)

 

Chemo status (%)

117 (26.1)

156 (34.2)

0.009

 No

   

 Yes

332 (73.9)

300 (65.8)