Table 1 Clinical characteristics of 1013 glioma patients in the CGGA dataset according to FCER1G expression levels
From: Prognostic and predictive value of FCER1G in glioma outcomes and response to immunotherapy
FCER1G expression | High | Low | P value |
|---|---|---|---|
n | 506 | 507 | Â |
FCER1G_mRNA (median [IQR]) | 6.74 [6.22, 7.42] | 4.69 [3.81, 5.22] | < 0.001 |
Age (median [IQR]) | 44.00 [36.00, 54.00] | 41.00 [34.00, 49.00] | 0.002 |
Gender (%) | Â | Â | 0.371 |
 Female | 199 (39.3) | 214 (42.2) |  |
 Male | 307 (60.7) | 293 (57.8) |  |
Grade (%) |  |  | < 0.001 |
 II | 101 (20.0) | 187 (36.9) |  |
 III | 140 (27.7) | 193 (38.1) |  |
 IV | 261 (51.6) | 126 (24.9) |  |
| Â | 4 ( 0.8) | 1 ( 0.2) | Â |
Histology (%) | Â | Â | Â |
 Anaplastic Astrocytoma | 118 (23.3) | 95 (18.7) |  |
 Anaplastic Oligoastrocytoma | 2 ( 0.4) | 19 ( 3.7) |  |
 Anaplastic Oligodendroglioma | 19 ( 3.8) | 75 (14.8) |  |
 Astrocytoma | 81 (16.0) | 92 (18.1) |  |
 GBM | 261 (51.6) | 126 (24.9) |  |
 Oligoastrocytoma | 2 ( 0.4) | 7 ( 1.4) |  |
 Oligodendroglioma | 19 ( 3.8) | 92 (18.1) |  |
| Â | 4 ( 0.8) | 1 ( 0.2) | Â |
Recurrence (%) | Â | Â | 0.001 |
 Primary | 296 (58.5) | 350 (69.0) |  |
 Recurrent | 186 (36.8) | 147 (29.0) |  |
 Secondary | 20 ( 4.0) | 10 ( 2.0) |  |
| Â | 4 ( 0.8) | 0 ( 0.0) | Â |
Subtype (%) |  |  | < 0.001 |
 Classical | 110 (21.7) | 52 (10.3) |  |
 Mesenchymal | 95 (18.8) | 19 ( 3.7) |  |
 Proneural | 82 (16.2) | 74 (14.6) |  |
| Â | 219 (43.3) | 362 (71.4) | Â |
survival (median [IQR]) | 17.50 [8.80, 40.60] | 37.00 [15.35, 75.85] | < 0.001 |
status (%) | Â | Â | Â |
 Alive | 125 (25.3) | 260 (53.1) | < 0.001 |
 Dead | 369 (74.7) | 230 (46.9) |  |
IDH status (%) |  |  | < 0.001 |
 Mutant | 213 (42.1) | 316 (62.3) |  |
 Wildtype | 287 (56.7) | 145 (28.6) |  |
| Â | 6 ( 1.2) | 46 ( 9.1) | Â |
1p19q (%) |  |  | < 0.001 |
 Codel | 39 ( 7.7) | 172 (33.9) |  |
 Non-codel | 461 (91.1) | 263 (51.9) |  |
| Â | 6 ( 1.2) | 72 (14.2) | Â |
Radio status (%) | 68 (14.9) | 94 (20.0) | 0.047 |
 No |  |  |  |
 Yes | 388 (85.1) | 376 (80.0) |  |
Chemo status (%) | 117 (26.1) | 156 (34.2) | 0.009 |
 No |  |  |  |
 Yes | 332 (73.9) | 300 (65.8) |  |