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Fig. 5 | Cancer Cell International

Fig. 5

From: Circular RNA CDR1as promotes tumor progression by regulating miR-432-5p/E2F3 axis in pancreatic cancer

Fig. 5

CircCDR1as promotes progression of pancreatic cancer by regulating E2F3 via miR-432-5p. a, b Western blot detected the expression of E2F3 in PANC-1, ASPC-1 cells transfected with NC inhibitor, miR-432-5p inhibitor, sh-circCDR1as + miR-432-5p inhibitor, NC mimic, miR-432-5p mimic and OE-circCDR1as + miR-432-5p mimic. c, e The migration and invasion of PANC-1, ASPC-1 cells transfected with NC inhibitor, miR-432-5p inhibitor, sh-circCDR1as + miR-432-5p inhibitor. d, f The proliferation of PANC-1, ASPC-1 cells transfected with NC inhibitor, miR-432-5p inhibitor and sh-circCDR1as + miR-432-5p inhibitor. g, h Knocking down of circCDR1as inhibited the growth of pancreatic cancer xenograft tumor (*p < 0.05, **p < 0.01)

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Cancer Cell International

ISSN: 1475-2867

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