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Fig. 2 | Cancer Cell International

Fig. 2

From: CircMMP11 regulates proliferation, migration, invasion, and apoptosis of breast cancer cells through miR-625-5p/ZEB2 axis

Fig. 2

The effects of circMMP11 inhibition on proliferation, migration, invasion, and apoptosis of breast cancer cells. a, b The expression of circMMP11 was measured by RT-qPCR assay in MCF-7 and MDA-MB-231 cells transfected with si-NC, si-circMMP11#1, si-circMMP11#2, or si-circMMP11#3. cj MCF-7 and MDA-MB-231 cells were transfected with si-NC or si-circMMP11#2. ce The proliferation ability of MCF-7 and MDA-MB-231 cells were estimated by MTT and colony-forming assays. f, g Transwell assay was conducted to assess migration and invasion of MCF-7 and MDA-MB-231 cells. h The apoptotic cells were monitored by flow cytometry assay. i, j The protein expression levels of E-cadherin and Vimentin were quantified by western blot assay. **P < 0.01, ***P < 0.001

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